Which Venice Neighborhood to Sleep in?

[grandcanyondave]

My wife and I (age 65) are planning a four night November stay in Venice . We'd like to make a few of our meals. I am hoping to find an apartment fairly close to a market and vaporetto stop. If possible, I'd prefer only one flight of stairs, super clean, with a view (but then, I'd also like a second home in Provence with a Porsche too).
There are so many apartments for rent that I'm uncertain which neighborhood to focus on. Any suggestions?