@Andrea_Stellato - hello and welcome here!
I was hoping that more forum members might chip in, as you've posed an interesting question. Sorry I can't contribute, as I have not travelled much in Italy, and when we do go, we mostly return to Piemonte. My Italian is also not good enough to seriously engage in a conversation with Italians.
I know there are regional differences because our hosts, and small producers that we meet, sometimes mention them. There is of course rivalry and humor about this - I was made aware of this both through the song "Genova per noi", and also when talking with disgruntled sellers in weekly markets that come from another region and complain about the locals.
If you meant only geographical differences, then I could only say that we find Italy's landscapes stunning wherever we go. I am sure that if we had picked Umbria for our first trip to Italy instead of Piemonte, then it would have been the place that we fell in love with and want to return to. We have also encountered amazing hospitality everywhere, not only from our hosts, but from complete strangers that are willing to go out of their way to help you. I am also very impressed by the fact that there is still much small-scale agriculture that is viable, in all the places we have visited.
So perhaps you would be willing to give your perspective on this - how does the area of Le Marche and its residents differ from other regions? If you compare to Piemonte, this would certainly intrigue me personally. Thanks